CURRICULUM  VITAE

PERSONAL INFORMATION

Name: ASSIA ANDRIANOVA KONSOULOVA-KIROVA, MD, DM

Date of Birth: December 21, 1978

Place of Birth: Sofia, Bulgaria

Home Address: № 2 Batak Str., apt.47, Varna, Bulgaria

CURRENT POSITIONS

Since May 2022 Chief of Medical Oncology Clinic, SHATO – Sofia

Since Mar 2022 Founder and member of the board of the Bulgarian Joint Cancer Network and Head of the Comprehensive Cancer centers, network connections and innovations

Since Mar 2021 Assoc. Prof. in Internal medicine, Department Preclinical and clinical disciplines, University Prof. Dr. A. Zlatarov – Burgas

Since 2019 Senior Medical Oncologist at Medical Oncology Clinic, Complex Oncological Center, Burgas, Bulgaria

Since December 2010 National ERS representative for the European Initiative in Quality Management in Lung Cancer Care for Bulgaria 

Since April 2012 Member of the ethical committee at the Society of the Young oncologists in Bulgaria

Since May 2018 Expert in the Scientific Board of the National Annual Scientific MORE conference, elaborating the National guidelines in Medical Oncology 

CONTACT INFORMATION

E-mail: dr.konsoulova@gmail.com

Mobile phone: –

EDUCATION

2021 Academic degree Associate professor in Internal medicine, University Prof. Dr. A. Zlatarov – Burgas

2016 PhD degree at MEDICAL UNIVERSITY – VARNA. PhD thesis in „Expression of some plasma and tissue biomarkers as potential predictors for anti-angiogenesis treatment in metastatic colorectal cancer.”

2015 DEGREE IN MEDICAL ONCOLOGY, Diploma № 3640

2011 DEGREE IN INTERNAL MEDICINE, Diploma № 3065

1997 – 2003                 MEDICAL UNIVERSITY – VARNA 

DEGREE IN MEDICINE, Diploma № 3343 / 2003

1992 – 1997 FIRST LANGUAGE SCHOOL – VARNA; 9751 / 1997

Profile: ENGLISH, FRENCH

INTERNSHIP and EDUCATIONAL COURSES

9-15 Jun 2019 Fellow of the MSKCC Seminar in Oncology / Open Medical Institute, Breast and Gynecological cancers, Salzburg, Austria

Jan-Jul 2018 Fellow of the European School of Oncology at Champalimaud Clinical Center, Lisbon, Portugal

Nov-Dec 2017 CECOG fellow at AKH Vienna, Austria

2017 CECOG Immunotherapy Academy at Vienna, Austria

Advanced course in Immunology, Kiel, Germany

2015 Advanced Course in Diagnosis and Treatment of Neuroendocrine Tumors,

Uppsala, Sweden

2015 EXCEMED Masterclass in Molecular Oncology, Prague, Czech Republic

2014 Methods in Clinical Reserach 2014, FLIMS, Switzerland

2014 ESO-ESMO Balkan Region Masterclass, Brdo, Slovenia

2013/2014 ESO Breast cancer update course, part I and II, Lisbon/Milan

2011 ESO First Balkan Masterclass in Oncology, Dubrovnik

Apr-May 2010 ESMO grant for Clinical Unit visit 2010 in “Jules Bordet” Institute, Brussels, Belgium

POSITION AND HONOURS

Past positions

2004 – 2018 Assistant in Internal Medicine and Medical Oncology, Bulgarian and English speaking students, Medical University „Prof. Dr. P. Stoyanov”, Varna, Bulgaria

2004 – 2019 Medical Oncologist at the Medical Oncology Clinic, University Hospital “Sveta Marina”, Varna, Bulgaria

2006 – 2007 Resident in Medical oncology at “Jules Bordet” Institute with a grant FOSFOM for 1-year education at the Free Brussels University (ULB), Belgium

April-September 2005 Assistant in the Medical Oncology clinic at the Institute “Jules Bordet”, Brussels, Belgium

2004 – 2010 Resident in Internal Medicine, University Hospital “Sveta Marina”, Varna, Bulgaria

2002 – 2003 Clinical student’s practice in the III Clinic of Internal medicine – Friedrichstadt General Hospital, Dresden, Germany.

Honors 

2019 ESMO Merit Award for ESMO Breast cancer 2019, Berlin, Germany

2018 ESO Clinical Training Fellowship for 6 months

2016 MORE-Darzalas annual award for achievements and significant input to Bulgarian Clinical Oncology

2014 Favorite lecturer of English-speaking Students at the Medical University – Varna for 2013 / 2014

2012 First National grant for young physicians who stay and practice in Bulgaria “Teodora Zaharieva”

SCIENTIFIC AND MEDICAL SOCIETIES

Since 2013 Member of the National expert council for Medical Oncology

Since 2013 Member of ECCO

Since 2012 Member of ASCO; ID 274000

Since 2011 Founder and a member of the board of the NATIONAL SCIENTIFIC SOCIETY FOR MEDICAL ONCOLOGY

2011 – 2016 Secretary of the First board for Neuroendocrine tumors at the University hospital “Sveta Marina” – Varna

Since 2008 Member of ESMO; Member of the YOC of ESMO; ESMO ID 21942

Since 2007 Member of the Bulgarian Oncological Society

Since 2004 Member of the Society of the Young Oncologists in Bulgaria

2004 MEDICAL UNIVERSITY – VARNA

Member of the scientific research commission at the university

OTHER MEMBERSHIP AND ACTIVITIES

2014 – 2017 Responsible for ENTYAC (European network for teenagers and young adults with cancer) for Bulgaria

2013 – 2014 Member of the National expert council for Medical Oncology at the Health ministry

2012 – 2016 Coordinator of the First National NEUROENDOCRINE TUMOUR BOARD, held at “Sveta Marina” University Hospital, Varna

2011 – 2017 Founder and a member of the administrative council of the NATIONAL SCIENTIFIC SOCIETY FOR MEDICAL ONCOLOGY

RESEARCH PROJECTS 

Aug 2018 Male Breast cancer. Collection and analysis of data from the National Bulgarian cancer registry. 

Oct 2018 Male breast cancer – International MBC Balkan collaborative project.

Aug 2018 Male Breast cancer. Collection and analysis of data from the National Bulgarian cancer registry. 

Oct 2018 Male breast cancer – International MBC Balkan collaborative project.

May 2015 Apoptosis in cancer – potential predictive markers and clinical correlations

Since 2015 Bevacizumab in combination with chemotherapy as first-line therapy in metastatic/locally recurred breast cancer, lung or colorectal cancer and identification of potential predictive biomarkers

List of selected publications 

1. H. Gouveia, A. Konsoulova, Cardoso F. New strategies for the precision treatment of HER2-driven tumours. Expert Review of Precision Medicine and Drug Development, 2019. DOI: 10.1080/23808993.2019.1626713
2. A. Konsoulova, I. Donev, N. Conev, I. Tonev, D. Kalev. Antiangiogenic treatment – rationale, mechanisms of action and clinical implications in Medical oncology. Journal of Bulgarian Oncological Society, 2015;(2):3-14.
3. А. Konsoulova, I. Donev, N. Tzonev, E. Dimitrova, A. Hristova, S. Draganova, Kr. Kirov. Immunological mechanisms, types of immunotherapy and mechanisms in solid tumors. Studia Oncologica, 2015;(1):29-48.
4. Kr. Kirov, I. Gavrilova, А. Konsoulova. Immunology and modern immunotherapy in malignant melanoma. Studia Oncologica, 2015;(1):9-27.
5. G. Kurteva, I. Trifonova, A. Konsoulova. Pregnancy, anti-tumor therapy and fetal health. Journal Oncology, 2013:41(4):46-48
6. А. Konsoulova, I. Donev, N. Tzonev, E. Dimitrova, I. Tonev, D. Kalev. Mechanisms of induced resistance to EGFR TKIs in patients with NSCLC – a review and our experience. Journal of Bulgarian oncologic society 2012;1:31-36.
7. А. Konsoulova, D. Kalev, I. Tonev. Cancer pain management – types of analgesia, standards and new perspectives. Journal of Bulgarian oncologic society 2008;4: 11-14
8. А. Konsoulova, Hr. Tsekov. Mechanisms of cytostatic-induced cardiotoxicity. Journal of Bulgarian oncologic society 2005;4: 11-14
9. M. Vassileva, S. Maslianokov, А. Vlahova, М. Genadieva, V. Pavlov, Z. Zahariev, D. Kostova-Lefterova, G. Todorov, А. Konsoulova, K. Angelov. Pathological response to preoperative systemic therapy – an achievable prognostic factor. A book of the XVI National surgery congress 2018;1: pp 632-642
10. I. Donev, N. Conev, A. Konsoulova, I. Tonev, T. Chervenkov, E. Dimitrova, D. Kalev. OCTA HGF/MET: mechanisms of tumor progression and drug resistance. Journal of Bulgarian oncologic society 2012;1:37-39
11. I. Donev, N. Conev, A. Konsoulova, T. Chervenkov, P. Genev, E. Dimitrova, D. Kalev. Phosphatidylinositol 3-kinases: from molecular pathology to the clinical target. Journal of Bulgarian oncologic society 2012;1:40-43
12. N. Tzonev, I. Donev, T. Chervenkov, P. Genev, E. Dimitrova, А. Konsoulova, D. Kalev. Influence of the micro-RNAs over the signal pathways in colorectal cancer. Journal of Bulgarian oncologic society 2012;1: 44-48.
13. D. Kalev, Zh. Mihaylova, I. Krasnaliev, D. Miteva, A. Konsoulova, I. Tonev, Yu. Raynov, А. Mihova. Possibilities for pharmacogenome-oriented treatment in non-small cell lung cancer. Journal of Bulgarian oncologic society 2008;1:4 -10

Publications in international and peer-review journals 

1. A. Konsoulova, K. Kalchev, A. Yordanov, S. El Shemeri, S. Strashilov, S. Masliankov, K. Angelov, D. Kostova-Lefterova, Y. Marincheva, M. Vasileva. Endocrine imlications in male breast cancer in Bulgaria. Annals of Oncology 2019; Abstr 36P
2. A. Konsoulova, A. Yordanov, D. Kostova-Lefterova, S. El Shemeri, M. Dimova, S. Strashilov, R. Hristova, S. Masliankov, Y. Marincheva, M. Vasileva. Adjuvant management of male breast cancer in Bulgaria. Annals of Oncology 2019; Abstr 98P.
3. A. Rich, D. Baldwin, P. Beckett, T. Berghmans, J. Boyd, C. Faivre-Finn, F. Galateau-Salle, F. Gamarra, B. Grigoriu, N.Hansen, G. Hardavella, E. Jakobsen, D. Jovanovic, A. Konsoulova, G. Massard, J. McPhelim, A-P. Meert, R. Milroy, L. Mutti, M. Paesmans, M. Peake, P.M. Putora, D. de Ruysscher, J-P. Sculier, A. Schepereel, D. Subotic, P. Van Schil, T. Blum. ERS Statement on harmonised standards for lung cancer registration and lung cancer services in Europe. European Respiratory Journal 2018; 52(4): 1800610; DOI: 10.1183/13993003.00610-2018
4. A. Rich, D. Baldwin, I. Alfageme, P. Beckett, T. Berghmans, S. Brincat, O. Burghuber, A. Corlateanu, T. Cufer, R. Damhuis, E. Danila, J. Domagala-Kulawik, S. Elia, M. Gaga, T. Goksel, B. Grigoriu, G. Hillerdal, R. Huber, E. Jakobsen, S. Jonsson, D. Jovanovic, E. Kavcova, A. Konsoulova, T. Laisaar, R. Makitaro, B. Mehic, R. Milroy, J. Moldvay, R. Morgan, M. Nanushi, M. Paesmans, PM. Putora, M. Samarzija, A. Scherpereel, M. Schlesser, JP Sculier, J. Skrickova, R. Sotto-Mayor, TE. Strand, P. Van Schil and T. Blum. Achieving Thoracic Oncology data collection in Europe: a precursor study in 35 Countries. BMC Cancer 2018;18:1144
5. D Stark, S Bielack, L Brugieres, U Dirksen, X Duarte, Dunn S, DJ Erdelyi, T Grew, L Hjorth, J Jazbec, E Kabickova, A Konsoulova, Kowalczyk JR, Lassaletta A, Laurence V, Lewis I, Monrabal A, Morgan S, G Mountzios, PR Olsen, M Renard, G Saeter, van der Graaf WT and A. Ferrari. European Journal of Cancer Care Teenagers and Young Adults with Cancer in Europe: from national programs to an European integrated coordinated project. European Journal of Cancer Care 2016. 25(3): 419-427.
6. A. Konsoulova-Kirova, I. Donev, N. Conev, S. Draganova, N. Petrova, E. Dimitrova, H. Popov, K. Bratieva, P. Ghenev. First line 5-Fu-based chemotherapy with/without Bevacizumab for Metastatic Colorectal Cancer: tissue biomarker candidates. Journal of IMAB – Annual Proceeding (Scientific Papers) 2016; 22(1):1039-1044
7. A. Konsoulova, I. Donev, N. Conev, S. Draganova, T. Chervenkov, N. Petrova, E. Dimitrova, P. Genev, Ya. Kashlov, D. Kalev. First line 5-FU-Based chemotherapy with/without bevacizumab for metastatic colorectal cancer: One center experience results. Scripta Scientifica Medica, 2015;47(1): 20-25
8. N. Conev, I. Donev, E Dimitrova, M Kozhuharova, M. Georgieva, A Konsoulova-Kirova, D. Kalev. 2-year single center clinical experience in patients with colon cancer stage II and III receiving adjuvant chemotherapy. Scripta Scientifica Medica 2015;47(2):43-48
9. N. Conev N, I. Donev, А. Konsoulova-Kirova, T. Chervenkov, J. Kashlov, K. Ivanov.  Serum expression levels of miR-17, miR-21, and miR-92 as potential biomarkers for recurrence after adjuvant chemotherapy in colon cancer patients. BioScience Trends. 2015 ;9(6):393-401. 
10. T. Blum, A. Rich, D. Baldwin, P. Beckett, D. Ruysscher, C. Faivre-Finn, M. Gaga, F. Gamarra, B. Grigoriu, N. Hansen, R. Hubbard, R Huber, E. Jakobsen, D. Jovanovic, A. Konsoulova, J. Kollmeier, G. Massard, J. McPhelim, A-P. Meert, R. Milroy, M. Paesmans, M. Peake, P-M Putora, A Scherpereel, N. Schönfeld, H Sitter, K Skaug, S. Spiro, T-E Strand, S. Taright, M. Thomas, P. van Schil, JF. Vansteenkiste, R. Wiewrodt, J-P. Sculier. The European initiative for quality management in lung cancer care. European Respiratory Journal 2014;43:1254-1277
11. M. Petrova, K. Hristozov, А. Konsoulova, D. Kalev. Sunitinib-induced hypothyroidism – a case report and a review of the literature. European Thyroid Journal 2011; p 181 (abstract). DOI:10.1159/000330565.

Book chapters

1. S Volovat, JM Ribeiro, A. Konsoulova, Paluch-Shimon S, Cardoso F. Management of advanced breast cancer in young women: what’s new in systematic treatment? Book chapter to be published in Breast cancer in young women. Oreste Gentilini, Ann H. Partridge and Olivia Pagani (Eds) Springer International publishing. (accepted for publication in Jan 2019)
2. А. Konsoulova, M. Vassileva. Update on the current management of breast cancer in men. A book chapter in: Continuous Medical Education Study book of National conference MORE 2018. ISBN 978-619-7094-38-1. pp 91-117
3. K. Koynov, A. Konsoulova, N. Dimitrova, D. Toncheva. General risk assessment and risk-reducing approaches. A chapter of the National Guidelines for Breast cancer, version 2.2018. Ed: D. Kalev. ISBN: 978-619-7094-43-5; pp 12-16
4. А. Konsoulova. What could we expect from the systemic treatment in hormone receptor positive metastatic breast cancer? A book chapter in: Continuous Medical Education Study book of the National conference MORE 2018. ISBN 978-619-7094-38-1. pp 75-89
5. A. Konsoulova, D. Toncheva, I. Gavrilov, S. Popovska. Assessment, consultation and genetic risk reduction. A chapter of the National Guidelines for Breast cancer, version 2.2018. Ed: D. Kalev. ISBN: 978-619-7094-43-5; pp 22-28
6. K. Koynov, A. Konsoulova. Risk-reducing endocrine treatment. A chapter of the National Guidelines for Breast cancer, version 2.2018. Ed: D. Kalev. ISBN: 978-619-7094-43-5; pp 195-201
7. A. Konsoulova, G. Kurteva, S. Gancheva. Management of hormone-receptor positive HER2-negative metastatic or locally recurred breast cancer. A chapter of the National Guidelines for Breast cancer, version 2.2018. Ed: D. Kalev. ISBN: 978-619-7094-43-5; pp 213-224
8. A. Konsoulova, G. Kurteva, K. Koynov. Systemic chemotherapy for triple negative metastatic breast cancer. A book chapter in the National breast cancer guidelines in Bulgarian Oncology, MORE 2018, Ed: D. Kalev. ISBN: 978-619-7094-43-5; pp 264-277
9. A. Konsoulova,  K. Koynov, G. Kurteva. Management of male breast cancer. A chapter of the National Guidelines for Breast cancer, version 2.2018. Ed: D. Kalev. ISBN: 978-619-7094-43-5; pp 282-292
10. A. Konsoulova. Predictive biomarkers in oncology – hopes and scepsis. Predictive biomarkers in oncology – tests and clinical use. A book chapter in: Continuous Medical Education book of the National conference MORE 2017. ISBN 978-619-7094-33-6; pp 6-16
11. A. Konsoulova, F. Cardoso. Management of male breast cancer. A book chapter to be published in Bonadonna’s Textbook of Breast Cancer 4E: A Clinical Guide to Therapy. L. Gianni, G. Sledge, P.Valagussa (Eds). (submitted for publication in 2018)
12. I. Donev, N Kolev, V. Ignatov, A. Tonev, A Zlatarov, A. Konsoulova, E. Entcheva, P. Drenakova and K. Ivanov. Adjuvant treatment in colon cancer. A book chapter in Colon cancer. Luis Rodrigo (Ed.). September 2016. ISBN 978-953-51-2544-0. pp:271-282
13. Kr. Kirov, А. Konsoulova. Target and immunotherapy strategies in advanced cutaneous melanoma and other skin tumors – management algorhythms. A chapter of the National Guidelines for Skin tumors and malignant melanoma, 2015. Ed: D. Kalev. ISBN: 978-619-7094-14-5. pp 167-175.
14. A. Konsoulova. Principles of cancer immunobiology and immunotherapy of solid tumors. A book chapter in Immunopathology and immunomodulation. Kr. Metodiev (Ed.) Nov, 2015. ISBN: 978-953-51-2210-4. http://dx.doi.org/10.5772/61211; pp 77 – 100.
15. G. Kurteva, А. Konsoulova, I. Trifonova. Treatment algorhythms in HER2 positive early and advanced breast cancer. A book chapter in: Continuous Medical Education Study book of National conference MORE 2013. Ed: D. Kalev. ISBN: 978-619-7094-04-6, pp 163-174.

REFEREEING ACTIVITIES

Scripta Scientifica Medica Journal

Abstract reviewer for the ERS International congress since 2016

ERS Journal Breath; Journal of Disease and Global Health since 2016.

ADDITIONAL INFORMATION

 LANGUAGE SKILLS

Spoken Written

Bulgarian (native) Excellent Excellent

English Excellent Excellent

French Excellent Excellent

German Good Good

Russian Good Good 

Portuguese Basic Basic

Licensed simultaneous interpreter from/to English language